NP-RD30 — R&D Tablet Press with Production-Level Compression

Stop lab-scale surprises before they reach production.

The Natoli NP-RD30 combines production-level compression mechanics with integrated AIM™ Pro data acquisition and analysis software, allowing researchers to evaluate formulations under realistic manufacturing conditions — without leaving the lab.

The result: production-representative data, deeper formulation insight, and greater confidence during scale-up.

Electronic Encapsulation Machine at Natoli Engineering

Close Up of Compression Zone on NP-RD30 Tablet Press Machine

Close Up of NP-RD30 Tablet Press Machine Wiring and Process

Close Up of Inside Electrical of NP-RD30 Tablet Compression Machine

NP-RD30 Tablet Compression Machine Close Up of Fill Positions

Built for Production-Representative R&D

Simulate real manufacturing conditions in a controlled research environment.

Production-level turret speeds and punch velocity
Realistic dwell time and compression forces
Accurate modeling of die fill and powder flow behavior

Analyze Compaction Behavior Under Real Conditions

Generate data that reflects true production performance.

Study effects of turret speed, dwell time, and feeder configuration
Evaluate formulation behavior under realistic compression conditions
Capture production-relevant, velocity-based data during R&D

Integrated Compaction Analysis with AIM™ Pro

The NP-RD30 includes AIM™ Pro software, transforming the press into a fully instrumented analytical platform.

Capture compression, ejection, and process data in real time
Analyze formulation behavior under dynamic conditions
Normalize force (kN) to pressure (MPa), enabling consistent analysis and predictability across different tablet sizes

AIM™ Pro generates the analytical models required for formulation development:

Tabletability
Compactibility
Compressibility
Strain rate profiles
Ejection force analysis

Make Confident, Data-Driven Scale-Up Decisions

Reduce risk and improve predictability in manufacturing.

Identify formulation limitations before production
Optimize feeder speed, feeder configuration, dosing, compression settings, and tablet thickness
Reduce trial-and-error during scale-up
Generate production-representative data from lab studies

Reduce variability and eliminate surprises during scale-up.

Flexible Operation for R&D and Pilot Production

Adapt to multiple development stages.

Single-tablet mode for minimal API testing
Multi-station turret configurations (up to 15+)
High-throughput capability for pilot batches

Designed for Consistent, Production-Representative Results

Built to deliver repeatable performance that mirrors manufacturing conditions.

Gravity feed or dual-paddle force feeder
Optimized fill cam design
Separate mechanical and compression zones
Dual vacuum system with powder recirculation
21 CFR Part 11 compliant system
21” touchscreen HMI with USB data transfer

Applications

Formulation development and screening
Compaction and compression studies
Process scale-up and optimization
Clinical trial and pilot production
USP <1062> studies

Technical Overview

Main Compression Force: Up to 60 kN
Pre-Compression: 10 kN
Speed: 10–100 RPM
Stations: 4–22 configurations
Output: 2,400–132,000 tablets/hour
Max Tablet Diameter: ~23.8 mm
Max Fill Depth: ~20–22 mm

Bridge the Gap Between Lab and Production

The NP-RD30 connects research data directly to manufacturing outcomes — with integrated analytics that support confident scale-up.

Set the Date. See the Data. Validate Your Formulation.

Bring production realism into your R&D process.

Request a Quote or Demonstration

Connect with Natoli’s technical team to discuss pricing, compatibility, or a live demonstration of the NP-RD30 for your research and development environment.